Publications

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Accelerated epigenetic aging and prospective morbidity and mortality among U.S. veterans
Bourassa KJ, Anderson L, Woolson S, Dennis PA, Garrett ME, Hair L, Dennis M, Sugden K, Williams B, Houts R, Calhoun PS, Naylor JC, Ashley-Koch AE, Beckham JC, Caspi A, Taylor GA, Hall KS, Moffitt TE, Kimbrel NA, VA Mid Atlantic MIRECC Workgroup
In Press. Journal of Gerontology: Medical Sciences.
Examining the timing of trauma, PTSD onset, and DNA methylation: A multicohort investigation of candidate CpG sites.
Bourassa, K. J., Garrett, M. E., Hair, L., Dennis, M. F., Sugden, K., Williams, B., Houts, R. M., Meier, M. H., VA Mid Atlantic MIRECC Workgroup,Beckham, J. C., Ashley-Koch, A. E., Theodore, R. F., Poulton, R. G., Moffitt, T. E., Caspi, A., & Kimbrel, N. A.
In Press. Journal of Psychiatric Research..
PTSD and suPAR: A multicohort investigation of chronic inflammation
Bourassa, K. J., Moffitt, T. E., Arseneault, L., Barrett-Young, A., Danese, A., Garrett, M. E., Houts, R. M., Matthews, T., Poulton, R., Ramrakha, S., Sprinckmoller, S., Sugden K, Williams, B.S., Beckham, J. C., Ashley-Koch, A. E., Kimbrel, N. A., Theodore, R. F., Caspi, A., & Rasmussen, L. J. H.
In Press. Brain, Behavior, and Immunity.
Longer residence in disadvantaged neighborhoods predicts both a syndrome of despair and deaths of despair: Complementary evidence from nationwide register and birth-cohort studies.
Reuben A, Milne B, Shah D, Brennan G, Richmond-Rakerd L.S., Guiney H., Harrington H., Hobbs M, Houts R, Ramakrishnan M, Ramrakha S, Theodore M, Caspi A., & Moffitt TE.
In Press. Clinical Psychological Science.
Accelerated biological aging and midlife frailty among U.S. military veterans
Bourassa, K. J., Dillon, K. H., Rodriguez, R. L., Garrett, M. E., Anderson, L., Dennis, P. A., Moffitt, T. E., Caspi, A., Cohen, H. J., Hall, K. S., Taylor, G. A., Naylor, J. C., Ashley-Koch, A. E., Beckham, J. C., & Kimbrel, N. A. for the VA Mid Atlantic MIRECC Workgroup.
2026. The Journals of Gerontology, Series A: Biological Sciences.
Cross-Tissue comparison of epigenetic aging clocks in humans
Apsley AT, Ye Q, Caspi A, Chiaro C, Etzel L, Hastings WJ, Heim CC, Kozlosky J, Noll JG, Schreier HMC, Shen CE, Sugden K, Shalev I
2025. Aging Cell.
Pace of Aging in older adults matters for healthspan and lifespan
Balachandran A, Pei H, Shi Y, Beard J, Caspi A, Cohen A, Domingue BW, Eckstein Indik C, Ferrucci L, Furuya A, Kothari M, Moffitt TE, Ryan C, Skirbekk V, Zhang Y, Belsky DW.
2025. Nature Aging .
Measures of retinal health successfully capture risk for Alzheimer's disease and related dementias at midlife
Barrett-Young A, Reuben A, Caspi A, Cheyne K, Ireland D, Kokaua J, Ramrakha S, Tham Y-C, Theodore R, Wilson G, Wong TY, Moffitt TE
2025. Journal of Alzheimer’s Disease .
Why psychopathology research should avoid studying one mental disorder at a time: An intergenerational and developmental evidence base for understanding ‘p’
Caspi A, Houts RM, Tegner Anker AS, Richmond-Rakerd L, Andersen SH, Theodore R, Poulton R, Moffitt TE, Torvik FA
2025. Journal of Psychopathology and Clinical Science.
Are Wednesday's children full of woe? Children's differences in personality are independent of day of birth
Wood E, Brown A, Wilding K, Oxley FAR, Fisher HL, Arseneault L, Caspi A, Moffitt TE, von Stumm S.
2025. Journal of Personality.
Quantifying the impact of early-life growth adversity on later-life health
Goldman-Pham R, Alter MP, Bao R, Collins SÉ, Debban CL, Allinson JP, Ambler A, Bertoni AG, Caspi A, Lovinsky-Desir S, Ekstrom MP, Engert JC, Jacobs DR Jr, Malinsky D, Manichaikul A, Michos ED, Moffitt TE, Oelsner EC, Ramrakha S, Rich SS, Sack C, Stanojevic S, Subbarao P, Sugden K, Theodore R, Watson KE, Williams B, Yang B, Dupuis J, Shaheen SO, Barr RG, Hancox RJ, Smith BM.
2025. Nature Communications Medicine.
Prediction of mental health risk in adolescents
Hill ED, Kashyap P, Raffanello E, Wang Y, Moffitt TE, Caspi A, Engelhard M, Posner J
2025. Nature Medicine.
Cognitive Abilities and Educational Attainment as Antecedents of Mental Disorders: A Total Population Study of Males
Nordmo M, Sunde HF, Kleppesto TH, Nordmo M, Caspi A, Moffitt TE, Torvik FA
2025. Psychological Science.
Social media use, online experiences, and loneliness among young adults: A cohort study
Matthews T, Arseneault L, Bryan BT, Fisher HL, Gray R, Henchy J, Moffitt TE, Odgers CL
2025. ANNALS of the New York Academy of Sciences.
New diagnosis in Psychiatry: Beyond Heuristics
McGorry PD, Hickier IB, Kotov R, Schmaal L, Wood SJ, Allan SM, Altinbas K, Boyce N, Fringmann LF, Caspi A, Cuthbert B, Gaweda L, Groen RN, Guloksuz S, Hartmann JA, Krueger RF, Mei C, Nieman D, Ongur D, Raballo A, Scheffer M, Schreuder MJ, Shah JL, Wigman JTW, Yuen HP, Nelson B.
2025. Psychological Medicine.
DNA methylation profiles of long-term cannabis users in midlife: A comprehensive evaluation of published cannabis-associated methylation markers in a representative cohort
Meier M, Sugden K, Moffitt TE, Williams B, Bourassa K, Ramrakha S, Theodore R, Caspi A
2025. Molecular Psychiatry.
Mental health conditions are associated with increased risk of subsequent self-harm, assault and unintentional injuries in two nations
Richmond-Rakerd, L., Milne, B., Houts, R., Davie, G., D'Souza, S., Goldman-Mellor, S., Khalifeh, L., Caspi, A., Moffitt, T., Torvik, F.
2025. Nature Mental Health.
A methylome-wide association study of major depression with out-of-sample case-control classification and trans-ancestry comparison.
Shen X, Barbu M, Caramaschi D, Arathimos R, Czamara D, David F, Dearman A, Dilkes E, Herrera-Rivero M, Huider F, Kühn L, Lu K-C, Palviainen T, Schowe A, Shireby G, Weihs A, Wong C, Davyson E, Casey H, Adams M, Allgaier A-K, Barber M, Burrage J, Caspi A, Costeira R, Dunn E, Feldmann L, Frank J, Freisleder F, Gadd D, Greimel E, Hannon E, Harris S, Homuth G, Howard D, Iurato S, Korhonen T, Lu T-P, Martin N, Martins J, McDermott E, Meinert S, Navarro P, Ollikainen M, Pehl V, Piechaczek C, Scherff A, Stein F, Streit F, Teumer A, Völzke H, Dongen J, Walker R, Yusupov N, Arseneault L, Bell J, Berger K, Binder E, Boomsma D
Cox S, Dannlowski U, Evans K, Fisher H, Forstner A, Grabe H, Kaprio J, Kircher T, Kopf-Beck J, Kumari M, Kuo P-H, Li Q, Moffitt T, Mulcahy H, Murphy T, Schulte-Körne G, Mill J, Lewis C, BeCOME Working Group, OPTIMA Working Group, PGC MDD Working Group, Wray N, McIntosh A
2025. Nature Mental Health.
Parental income and psychiatric disorders from age 10 to 40: A genetically informative population study
Sunde, HF, Eilertsen EM, Kinge JM, Kleppesto TH, Nordmo M, Caspi A, Moffitt TE, Torvik FA
2025. Journal of Child Psychology and Psychiatry.
The nature of the relationship between mental well-being and ill-being
Tamnes, C.K., Bekkhus, M., Eilertsen, M. et al.
2025. Nature Human Behavior.
Building the world’s first truly global medical foundation model
Tham YC, Goh JHL, Deritu P, Zhou Y, Ran AR, Srinivasan S, Yang GD, Kitema GF, Rawlinson P, Jiang H, Cheung CY, Keane PA, Global RETFound Consortium
2025. Nature Medicine.
Genome-wide association meta-analysis of childhood ADHD symptoms and diagnosis identifies new loci and potential effector genes
van der Laan, C.M., Ip, H.F., et al.
2025. Nature Genetics.
Parenting in childhood predicts personality in early adulthood: A Longitudinal Twin-Differences Study
Wertz J, Moffitt TE, Caspi A, Blangis F, Arseneault L, Danese A, Fisher H, Amber, A
2025. American Psychologist.
DunedinPACNI estimates the longitudinal pace of aging from a single brain image to track health and disease
Whitman, ET, Elliott ML, Knodt AR, Abraham WC, Andersen TJ, Cutfield N, Hogan S, Ireland D, Melzer TR, Ramrakha S, Sugden K, Theodore R, Williams BS, Caspi A, Moffitt TE, Hariri AR
2025. Nature Aging.
Maternal expressed emotion and adolescent mental health: Using longitudinal monozygotic twin-difference analyses to approach causal inference
Wickersham A, Caspi A, Arseneault L, Moffitt TE, Downs J, Ambler A, Latham RM, Cummins N, Chritensen H, Firth Z, Fisher HL.
2025. Journal of Child Psychology and Psychiatry.