Gene X Environment: Empirical Studies

  • 5-HTTLPR and use of antidepressants after colorectal cancer including a meta-analysis of 5-HTTLPR and depression after cancer

    Suppli N, Bukh J, Moffitt TE, Caspi A, Johansen C, Albieri V, Tjønneland A, Kessing L, Dalton S
    2015 Translational Psychiatry 5:e631
    PDF icon PDF of Full Article

  • Serotonin transporter gene moderates childhood maltreatment's effects on persistent but not single-episode depression: Replications and implications for resolving inconsistent results

    Uher R, Caspi A, Houts R, Sugden K, Williams B, Poulton R, Moffitt TE
    2011 Journal of Affective Disorders 135:56-65
    http://www.ncbi.nlm.nih.gov/pubmed/21439648

  • Serotonin transporter gene moderates the development of emotional problems among children following bullying victimization

    Sugden K, Arseneault L, Harrington H, Moffitt TE, Williams B, Caspi A
    2010 Journal of the American Academy of Child & Adolescent Psychiatry 49:830-840
    http://www.ncbi.nlm.nih.gov/pubmed/20643316

  • Protective effect of CRHR1 gene variants on the development of adult depression following childhood maltreatment: Replication and extension.

    Polanczyk G, Caspi A, Williams B, Price TS, Danese A, Sugden K, Uher R, Poulton R, Moffitt TE
    2009 Archives of General Psychiatry Sep;66(9):978-85
    http://www.ncbi.nlm.nih.gov/pubmed/19736354

  • Moderation of breastfeeding effects on the IQ by genetic variation in fatty acid metabolism

    Caspi A, Williams B, Kim-Cohen J, Craig IW, Milne BJ, Poulton R, Schalkwyk LC, Taylor A, Werts H, Moffitt TE
    2007 Proceedings of the National Academy of Sciences Nov 20;104(47):18860-5
    http://www.ncbi.nlm.nih.gov/pubmed/17984066

  • MAOA, maltreatment, and gene-environment interaction predicting children's mental health: New evidence and a meta-analysis

    Kim-Cohen J, Caspi A, Taylor A, Williams B, Newcombe R, Craig IW, Moffitt TE
    2006 Molecular Psychiatry Oct;11(10):903-13
    http://www.ncbi.nlm.nih.gov/pubmed/16801953

  • Moderation of the effect of adolescent-onset cannabis use on adult psychosis by a functional polymorphism in the catechol-O-methyltransferase gene: Longitudinal evidence of a gene X environment interaction

    Caspi A, Moffitt TE, Cannon M, McClay J, Murray R, Harrington H, Taylor A, Arseneault L, Williams B, Braithwaite A, Poulton R, Craig IW
    2005 Biological Psychiatry May 15;57(10):1117-27
    http://www.ncbi.nlm.nih.gov/pubmed/15866551

  • Influence of life stress on depression: Moderation by a polymorphism in the 5-HTT gene

    Caspi A, Sugden K, Moffitt TE, Taylor A, Craig IW, Harrington H, McClay J, Mill J, Martin J, Braithwaite A, Poulton R
    2003 Science 301:386-389
    http://www.ncbi.nlm.nih.gov/pubmed/12869766

  • Role of genotype in the cycle of violence in maltreated children

    Caspi A, McClay J, Moffitt TE, Mill J, Martin J, Craig IW, Taylor A, Poulton R
    2002 Science 297:851-854
    http://www.ncbi.nlm.nih.gov/pubmed/12161658