Aging: Empirical Articles

  • White matter hyperintensities are common in midlife and already associated with cognitive decline

    d'Arbeloff, T, Elliott, ML, Knodt, AR, Melzer, TR, Keenan, R, Ireland, D, Ramrakha, S, Poulton, R, Anderson, T, Caspi, A, Moffitt, TE, Hariri, AR
    2020 Brain Communications
    PDF icon PDF of Full Article

  • Psychiatry's opportunity to prevent the rising burden of age-related disease

    Moffitt TE, Caspi A
    2019 JAMA Psychiatry
    PDF icon PDF of Full Article
    Best Articles of 2019

  • Association of neurocognitive and physical function with gait speed in midlife

    Rasmussen, LJH, Caspi, A, Ambler, A, Broadbent, JM, Cohen, HJ, d'Arbeloff, T, Elliott, M, Hancox, RJ, Harrington, HL, Hogan, S, Houts, R, Ireland, D, Knodt, A, Meredith-Jones, M, Morey, MC, Morrison, L, Poulton, R, Ramrakha, S, Richmond-Rakerd, L, Sison, ML, Sneddon, K, Thomson, WM, Hariri, AR, Moffitt, TE
    2019 JAMA Network Open
    PDF icon Fact Sheet, PDF icon Press Release, PDF icon PDF of Full Article, PDF icon Invited commentary by Dr. Stephanie Studenski

  • Eleven telomere, epigenetic clock, and biomarker-composite quantifications of biological aging: Do they measure the same thing?

    Belsky DW, Moffitt TE, Cohen AA, Corcoran DL, Levine ME, Prinz JA, Schaefer J, Sugden K, Williams B, Poulton R, Caspi A
    2017 American Journal of Epidemiology
    PDF icon Duke Press Release, PDF icon PDF of Full Article

  • Impact of early personal history characteristics on the pace of aging: Implications for clinical trials of therapies to slow aging and extend healthspan

    Belsky DW, Caspi A, Cohen HJ, Kraus WE, Ramrakha S, Poulton R, Moffitt TE
    2017 Aging Cell 16: 644-651
    PDF icon PDF of Full Article
    Article in Noted by Donna Chisholm

  • Lest we forget: Comparing retrospective and prospective assessments of adverse childhood experiences in the prediction of adult health

    Reuben A, Moffitt TE, Caspi A, Belsky DW, Harrington HL, Schroeder F, Hogan S, Ramrakha S, Poulton R, Danese A
    2016 Journal of Child Psychology and Psychiatry 57: 1103-1112
    PDF icon PDF of Full article

  • Cardiorespiratory fitness and cognitive function in midlife: Neuroprotection or neuroselection?

    Belsky DW, Caspi A, Israel S, Blumenthal JA, Poulton R, Moffitt TE
    2015 Annals of Neurology 77: 607-617
    PDF icon PDF of Full Article

  • Quantification of biological aging in young adults

    Belsky DW, Caspi A, Houts R, Cohen H, Corcoran DL, Danese A, Harrington HL, Israel S, Levine ME, Schaefer J, Sugden K, Williams B, Yashin AI, Poulton R, Moffitt TE
    2015 Proceedings of the National Academy of Sciences 112: 4104-4110
    PDF icon PDF of Full Article, PDF icon Fact Sheet, PDF icon Press Release, PDF icon Critique by Newman, PDF icon Reply to Newman
    Dan discussing Quantification of Biological Aging in Young Adults on BBC Newshour, Coverage in The Wall Street Journal, Article Impact by Altmetric, Coverage by The Onion (humor)

  • Early-life intelligence predicts midlife biological age

    Schaefer J, Caspi A, Belsky DW, Harrington HL, Houts R, Israel S, Levine M, Sugden K, Williams B, Poulton R, Moffitt TE
    2015 Journal of Gerontology: Psychological Sciences 71:968-977
    PDF icon PDF of Full Article

  • Perinatal complications and aging indicators by midlife

    Shalev I, Caspi A, Ambler A, Belsky DW, Chapple S, Cohen H, Salomon I, Poulton R, Ramrakha S, Rivera C, Sugden K, Williams B, Wolke D, Moffitt TE
    2014 Pediatrics 134:1315-1323
    PDF icon PDF of Full Article, PDF icon Editorial
    Commentary

  • Is chronic asthma associated with shorter leukocyte telomere length at midlife?

    Belsky DW, Shalev I, Sears MR, Hancox RJ, Harrington HL, Houts R, Moffitt TE, Sugden K, Williams B, Poulton R, Caspi A
    2014 American Journal of Respiratory and Critical Care Medicine 190:384-391
    PDF icon PDF of Full Article, PDF icon Editorial

  • Internalizing disorders and leukocyte telomere erosion: A prospective study of depression, generalized anxiety disorder and post-traumatic stress disorder

    Shalev I, Moffitt TE, Braithwaite AW, Danese A, Fleming NI, Goldman-Mellor S, Harrington HL, Houts R, Israel S, Poulton R, Robertson SP, Sugden K, Williams B, Caspi A
    2014 Molecular Psychiatry 1-8
    PDF icon PDF of Full Article

  • Retinal vessel caliber and neuropsychological functioning: An investigative tool for cognitive epidemiology

    Shalev I, Moffitt TE, Wong TY, Meier MH, Ding J, Cheung CY, Ikram KM, Caspi A, Poulton R
    2013 Psychological Science 24:1198-1207
    PDF icon PDF of Full Article
    Psychological Science Press Release