Karen Sugden, Ph.D.
Research Project Mgr, University
Karen graduated from the University of Liverpool with a B.Sc in genetics and received a Ph.D. from the Social, Genetic and Developmental Psychiatry (SGDP) Centre, King’s College London, focusing on the study of genetic and genomic influences on behavior and mental health. Her current appointment is with Duke University’s Department of Psychology and Neuroscience and Center for Genomic and Computational Biology.
Her current research focus is on the collection and analysis of biological information in large longitudinal cohorts. In particular, she is interested in applying cutting-edge molecular approaches to understand the biological mechanisms influencing normal and abnormal behavior. To this end, Karen is responsible for the curation and analysis of genetic, epigenetic and transcriptomic data in the Dunedin Longitudinal Study and the E-Risk Study. Karen also teaches and advises on methodological issues related to biomarker collection and analysis in population-based cohorts.
Away from the laboratory, Karen enjoys spending time in nature walking and bird-watching, as well as gardening, upholstery and trying to accumulate as many animals as is possible.
Sugden, Karen, et al. “Is Toxoplasma Gondii Infection Related to Brain and Behavior Impairments in Humans? Evidence from a Population-Representative Birth Cohort.” Plos One, vol. 11, no. 2, Jan. 2016, p. e0148435. Epmc, doi:10.1371/journal.pone.0148435. Full Text
Moffitt, Terrie E., et al. “Is Adult ADHD a Childhood-Onset Neurodevelopmental Disorder? Evidence From a Four-Decade Longitudinal Cohort Study.” The American Journal of Psychiatry, vol. 172, no. 10, Oct. 2015, pp. 967–77. Epmc, doi:10.1176/appi.ajp.2015.14101266. Full Text
Belsky, Daniel W., et al. “Quantification of biological aging in young adults.” Proc Natl Acad Sci U S A, vol. 112, no. 30, July 2015, pp. E4104–10. Pubmed, doi:10.1073/pnas.1506264112. Full Text Open Access Copy
Sugden, Karen, et al. “Blood Substrate Collection and Handling Procedures under Pseudo-Field Conditions: Evaluation of Suitability for Inflammatory Biomarker Measurement.” Biodemography and Social Biology, vol. 61, no. 3, Jan. 2015, pp. 273–84. Epmc, doi:10.1080/19485565.2015.1062717. Full Text
Shalev, I., et al. “Internalizing disorders and leukocyte telomere erosion: a prospective study of depression, generalized anxiety disorder and post-traumatic stress disorder.” Molecular Psychiatry, vol. 19, no. 11, Nov. 2014, pp. 1163–70. Epmc, doi:10.1038/mp.2013.183. Full Text
Shalev, Idan, et al. “Perinatal complications and aging indicators by midlife.” Pediatrics, vol. 134, no. 5, Nov. 2014, pp. e1315–23. Pubmed, doi:10.1542/peds.2014-1669. Full Text
Belsky, Daniel W., et al. “Is chronic asthma associated with shorter leukocyte telomere length at midlife?” American Journal of Respiratory and Critical Care Medicine, vol. 190, no. 4, Aug. 2014, pp. 384–91. Epmc, doi:10.1164/rccm.201402-0370OC. Full Text Open Access Copy
Belsky, Daniel W., et al. “Polygenic risk and the development and course of asthma: an analysis of data from a four-decade longitudinal study.” The Lancet. Respiratory Medicine, vol. 1, no. 6, Aug. 2013, pp. 453–61. Epmc, doi:10.1016/S2213-2600(13)70101-2. Full Text
Gunduz-Cinar, O., et al. “Convergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing and stress-reactivity.” Molecular Psychiatry, vol. 18, no. 7, July 2013, pp. 813–23. Epmc, doi:10.1038/mp.2012.72. Full Text
Shalev, I., et al. “Exposure to violence during childhood is associated with telomere erosion from 5 to 10 years of age: a longitudinal study.” Molecular Psychiatry, vol. 18, no. 5, May 2013, pp. 576–81. Epmc, doi:10.1038/mp.2012.32. Full Text