Karen Sugden

Karen Sugden

Research Project Mgr, University

+1 919 613 6996

Karen graduated from the University of Liverpool with a B.Sc in genetics and received a Ph.D. from the Social, Genetic and Developmental Psychiatry (SGDP) Centre, King’s College London, focusing on the study of genetic and genomic influences on behavior and mental health. Her current appointment is with Duke University’s Department of Psychology and Neuroscience and Center for Genomic and Computational Biology.

Her current research focus is on the collection and analysis of biological information in large longitudinal cohorts. In particular, she is interested in applying cutting-edge molecular approaches to understand the biological mechanisms influencing normal and abnormal behavior. To this end, Karen is responsible for the curation and analysis of genetic, epigenetic and transcriptomic data in the Dunedin Longitudinal Study and the E-Risk Study. Karen also teaches and advises on methodological issues related to biomarker collection and analysis in population-based cohorts.

Away from the laboratory, Karen enjoys spending time in nature walking and bird-watching, as well as gardening, upholstery and trying to accumulate as many animals as is possible.

Selected Grants

Comprehensive portrait of long-term cannabis users: Are they ready for old age? awarded by National Institutes of Health (Bioinformatics Specialist). 2020 to 2024

Social Relationship Qualities as Predictors of Health & Aging from Adolescence thru Midlife awarded by University of Virginia - Charlottesville (Principal Investigator). 2018 to 2022

Midlife Pace of Aging in the Dunedin Study awarded by King's College London (Research Professional). 2017 to 2021

Aging in 1000 healthy young adults: the Dunedin Study awarded by National Institutes of Health (Laboratory Technician). 2009 to 2021

Rasmussen, Line Jee Hartmann, et al. “Cumulative childhood risk is associated with a new measure of chronic inflammation in adulthood.Journal of Child Psychology and Psychiatry, and Allied Disciplines, vol. 60, no. 2, Feb. 2019, pp. 199–208. Epmc, doi:10.1111/jcpp.12928. Full Text

Hannon, Eilis, et al. “Characterizing genetic and environmental influences on variable DNA methylation using monozygotic and dizygotic twins.Plos Genetics, vol. 14, no. 8, Aug. 2018, p. e1007544. Epmc, doi:10.1371/journal.pgen.1007544. Full Text

Marzi, Sarah J., et al. “Analysis of DNA Methylation in Young People: Limited Evidence for an Association Between Victimization Stress and Epigenetic Variation in Blood.The American Journal of Psychiatry, vol. 175, no. 6, June 2018, pp. 517–29. Epmc, doi:10.1176/appi.ajp.2017.17060693. Full Text

Belsky, Daniel W., et al. “Eleven Telomere, Epigenetic Clock, and Biomarker-Composite Quantifications of Biological Aging: Do They Measure the Same Thing?American Journal of Epidemiology, vol. 187, no. 6, June 2018, pp. 1220–30. Epmc, doi:10.1093/aje/kwx346. Full Text

Wertz, J., et al. “Genetics and Crime: Integrating New Genomic Discoveries Into Psychological Research About Antisocial Behavior.Psychological Science, vol. 29, no. 5, May 2018, pp. 791–803. Epmc, doi:10.1177/0956797617744542. Full Text

Baldwin, Jessie R., et al. “Childhood victimization and inflammation in young adulthood: A genetically sensitive cohort study.Brain, Behavior, and Immunity, vol. 67, Jan. 2018, pp. 211–17. Epmc, doi:10.1016/j.bbi.2017.08.025. Full Text

Schaefer, Jonathan D., et al. “Early-Life Intelligence Predicts Midlife Biological Age.The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences, vol. 71, no. 6, Nov. 2016, pp. 968–77. Epmc, doi:10.1093/geronb/gbv035. Full Text

Belsky, Daniel W., et al. “The Genetics of Success: How Single-Nucleotide Polymorphisms Associated With Educational Attainment Relate to Life-Course Development.Psychological Science, vol. 27, no. 7, July 2016, pp. 957–72. Epmc, doi:10.1177/0956797616643070. Full Text Open Access Copy

Sugden, Karen, et al. “Is Toxoplasma Gondii Infection Related to Brain and Behavior Impairments in Humans? Evidence from a Population-Representative Birth Cohort.” Plos One, vol. 11, no. 2, Feb. 2016. Wos-lite, doi:10.1371/journal.pone.0148435. Full Text